hepatitis c virus genotypes
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چکیده
منابع مشابه
Hepatitis C virus infection and genotypes in blood donors
Abstract: Genotyping of the hepatitis C virus (HCV) is important for designing therapeutic strategies and regional specific diagnostic assays. The aim of this study was to identify the HCV genotypes in HCV infected blood donors. This is the first report on HCV genotypes in blood donors in Iran. In this cross-sectional study, 103 blood donors with hepatitis C were investigated for HCV genotype...
متن کاملClinical significance of hepatitis C virus genotypes.
The advent of genotyping assays has stimulated investigators around the world to study the molecular epidemiology of hepatitis C virus (HCV) infection in specific patient categories, as well as possible correlations with the clinical and histological features of chronic liver disease and response to antiviral treatment. While a general consensus has been reached on the worldwide epidemiology an...
متن کاملClinical Significance of Hepatitis C Virus Genotypes
INTRODUCTION .......................................................................................................................................................223 GENOMIC ORGANIZATION OF HCV..................................................................................................................223 GENOMIC HETEROGENEITY AND CLASSIFICATION SYSTEMS ......................................
متن کاملHepatitis C Virus: Viral Quasispecies and Genotypes
Hepatitis C virus (HCV) mainly replicates in the cytoplasm, where it easily establishes persistent infection, resulting in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Due to its high rate of mutation, HCV forms viral quasispecies, categorized based on the highly variable regions in the envelope protein and nonstructural 5A protein. HCV possesses seven major genotypes, amon...
متن کاملThe origin of hepatitis C virus genotypes.
For many RNA viruses, relatively recent times of origin of extant viruses are implied by the high rate of substitution observed in longitudinal studies. However, extrapolation of short-term rates of substitution can give misleading estimates of times of divergence. We show here that the common ancestor of different types of hepatitis C virus (HCV) is older than previously thought. The rate of H...
متن کاملMixed Genotypes in Hepatitis C Virus Infection
Before the existence of commercial clotting factor concentrates, bleeding was the number one cause of death in persons with hemophilia and the only alternative treatment was cryoprecipitate. During the 1970s human freeze-dried (lyophilized) FVIII and FIX became available. The life of individuals with hemophilia was revolutionized because patients were able to treat themselves conveniently at ho...
متن کاملDistribution of Hepatitis C virus genotypes in Yazd, Central Province of Iran: increasing the mixed genotypes
Background and Aims: Different hepatitis C virus (HCV) genotypes have characteristic geographical distribution. Identification of HCV genotype is an important factor in the progression, clinical outcome and therapy of HCV infection. The aim of this study was to determine the prevalence of HCV genotypes among HCV-RNA positive patients in Yazd, Iran. Materials and Methods: In this cross-sectiona...
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عنوان ژورنال:
hepatitis monthlyجلد ۲۰۱۶، شماره ۱۱، صفحات ۷۷-۸۲
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